Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      75 kDa including tags
    • Amino acids
      287 to 712

Specifications

Our Abpromise guarantee covers the use of ab125647 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    The specific activity of ab125647 was determined to be 83 nmol/min/mg.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity
    > 80 % Densitometry.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.002% PMSF, 0.005% DTT, 0.79% Tris HCl, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • 5''-cyclic phosphodiesterase 4C
    • cAMP specific 3' 5' cyclic phosphodiesterase 4C
    • cAMP-specific 3''
    • DPDE 1
    • DPDE1
    • MGC126222
    • PDE 21
    • PDE 4C
    • PDE21
    • Pde4c
    • PDE4C_HUMAN
    • Phosphodiesterase 4C
    • Phosphodiesterase 4C cAMP specific
    • Phosphodiesterase 4C, cAMP specific (phosphodiesterase E1 dunce homolog, Drosophila)
    • Phosphodiesterase E1 dunce homolog
    • Phosphodiesterase E1 dunce homolog Drosophila
    • Phosphodiesterase type 4C
    see all
  • Function
    Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
  • Tissue specificity
    Expressed in various tissues but not in cells of the immune system.
  • Pathway
    Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.
  • Sequence similarities
    Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
  • Information by UniProt

Images

  • SDS-PAGE analysis of ab125647.
  • Sample assay showing the specific activity of ab125647 to be 83 nmol/min/mg.

References

ab125647 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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