Recombinant Human PDE6 delta protein (ab117160)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH
    • Molecular weight
      18 kDa including tags
    • Amino acids
      1 to 150
    • Tags
      His tag C-Terminus
    • Additional sequence information
      PDE6D produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids (1-150 a.a.) and having a molecular mass of 18.4kDa.

Specifications

Our Abpromise guarantee covers the use of ab117160 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.
    ab117160 was purified by proprietary chromatographic techniques and filter sterilized.
  • Form
    Liquid
  • Additional notes
    For long term storage of ab117160 it is recommended to add a carrier protein (0.1% HSA or BSA).
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol, 0.02% DTT, 0.58% Sodium chloride

General Info

  • Alternative names
    • 5''-cyclic phosphodiesterase subunit delta
    • GMP PDE delta
    • GMP-PDE delta
    • p17 protein
    • PDE 6
    • PDE 6D
    • PDE D
    • PDE6
    • PDE6D
    • PDE6D_HUMAN
    • PDED
    • Phosphodiesterase 6D cGMP specific
    • Phosphodiesterase 6D cGMP specific rod delta
    • Protein p17
    • Retinal rod photoreceptor cGMP phosphodiesterase delta
    • Retinal rod rhodopsin sensitive cGMP 3' 5' cyclic phosphodiesterase subunit delta
    • Retinal rod rhodopsin-sensitive cGMP 3''
    see all
  • Function
    Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. Stabilizes Arl3-GTP by decreasing the nucleotide dissociation.
  • Tissue specificity
    Retina.
  • Sequence similarities
    Belongs to the PDE6D/unc-119 family.
  • Information by UniProt

References

ab117160 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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