The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
5''-cyclic phosphodiesterase 8A
cAMP specific cyclic nucleotide phosphodiesterase 8A
High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A
High affinity cAMP-specific and IBMX-insensitive 3''
Weakly similar to 3'5' cyclic nucleotide phosphodiesterase
FunctionHydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.
Tissue specificityExpressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon.