The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Dihydrolipoamide dehydrogenase binding protein of pyruvate dehydrogenase complex
Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex
E3 binding protein
Lipoyl containing pyruvate dehydrogenase complex component X
Lipoyl-containing pyruvate dehydrogenase complex component X
Pyruvate dehydrogenase complex component X
Pyruvate dehydrogenase complex lipoyl containing component X
Pyruvate dehydrogenase complex, E3 binding protein subunit
Pyruvate dehydrogenase protein X component
Pyruvate dehydrogenase protein X component mitochondrial
Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.
Involvement in disease
Defects in PDHX are the cause of pyruvate dehydrogenase E3-binding protein deficiency (PDHXD) [MIM:245349].
Belongs to the 2-oxoacid dehydrogenase family. Contains 1 lipoyl-binding domain.