Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionQ15084
    • SpeciesHuman
    • SequenceMGSSHHHHHH SSGLVPRGSH MLYSSSDDVI ELTPSNFNRE VIQSDSLWLV EFYAPWCGHC QRLTPEWKKA ATALKDVVKV GAVDADKHHS LGGQYGVQGF PTIKIFGSNK NRPEDYQGGR TGEAIVDAAL SALRQLVKDR LGGRSGGYSS GKQGRSDSSS KKDVIELTDD SFDKNVLDSE DVWMVEFYAP WCGHCKNLEP EWAAAASEVK EQTKGKVKLA AVDATVNQVL ASRYGIRGFP TIKIFQKGES PVDYDGGRTR SDIVSRALDL FSDNAPPPEL LEIINEDIAK RTCEEHQLCV VAVLPHILDT GAAGRNSYLE VLLKLADKYK KKMWGWLWTE AGAQSELETA LGIGGFGYPA MAAINARKMK FALLKGSFSE QGINEFLREL SFGRGSTAPV GGGAFPTIVE REPWDGRDGE LPVEDDIDLS DVELDDLGKD EL
    • Molecular weight49 kDa including tags
    • Amino acids20 to 440
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab101048 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry
    MALDI-TOF
  • Purity> 90 % SDS-PAGE.
    ab101048 is purified using conventional chromatography techniques
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0% None
    Constituents: 10% Glycerol, 50mM Sodium chloride, 20mM Tris HCl, 2mM DTT, pH 8.0

General Info

  • Alternative names
    • Endoplasmic reticulum protein 5
    • ER protein 5
    • ERp5
    • P5
    • Pdia6
    • PDIA6_HUMAN
    • Protein disulfide isomerase A6
    • Protein disulfide isomerase associated 6
    • Protein disulfide isomerase family A member 6
    • Protein disulfide isomerase P5
    • Protein disulfide isomerase related protein
    • Protein disulfide-isomerase A6
    • Thioredoxin domain containing 7 (protein disulfide isomerase)
    • Thioredoxin domain containing protein 7
    • Thioredoxin domain-containing protein 7
    • TXNDC7
    see all
  • FunctionMay function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.
  • Tissue specificityExpressed in platelets (at protein level).
  • Sequence similaritiesBelongs to the protein disulfide isomerase family.
    Contains 2 thioredoxin domains.
  • Cellular localizationEndoplasmic reticulum lumen. Cell membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

Recombinant Human PDIA6 protein images

  • ab101048 at 3 µg on an SDS-PAGE gel (15%)

References for Recombinant Human PDIA6 protein (ab101048)

ab101048 has not yet been referenced specifically in any publications.

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