Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • AccessionQ15120
    • SpeciesHuman
    • Molecular weight69 kDa including tags
    • Amino acids1 to 406

Specifications

Our Abpromise guarantee covers the use of ab125606 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityThe specific activity of ab125606 was determined to be 12 nmol/mg/min.
  • Applications

    Western blot

    Functional Studies

    SDS-PAGE

  • FormLiquid
  • Additional notes

    ab125602 (Human Pyruvate Dehydrogenase E1-alpha subunit full length protein) can be utilized as a substrate for assessing Kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • [Pyruvate dehydrogenase [lipoamide] kinase isozyme 3 mitochondrial
    • [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3
    • CMTX6
    • GS1-358P8.4
    • mitochondrial
    • PDK3
    • PDK3_HUMAN
    • Pyruvate dehydrogenase kinase isoenzyme 3
    • Pyruvate dehydrogenase kinase isoform 3
    • Pyruvate dehydrogenase kinase isozyme 3
    • Pyruvate dehydrogenase lipoamide kinase isozyme 3 mitochondrial
    see all
  • FunctionInhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
  • Tissue specificityFound almost exclusively in heart and skeletal muscle.
  • Sequence similaritiesBelongs to the PDK/BCKDK protein kinase family.
    Contains 1 histidine kinase domain.
  • Cellular localizationMitochondrion matrix.
  • Information by UniProt

Recombinant human PDK3 protein images

  • The specific activity of ab125606 was determined to be 12 nmol/mg/min by Kinase Assay.
  • SDS-PAGE analysis of ab125606.

References for Recombinant human PDK3 protein (ab125606)

ab125606 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"