Recombinant Human PRD protein (ab202165)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant Human PRD protein
See all PRD proteins and peptides -
Purity
> 90 % SDS-PAGE.
ab202165 was purified using conventional chromatography techniques. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MGSSHHHHHHSSGLVPRGSHMGSMAAATGPSFWLGNETLKVPLALFALNR QRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGV TEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQ YVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILH PEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFE HYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDM GGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWP DMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVH DVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALA DPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEA CMAGCDKAFTPFSGPK -
Predicted molecular weight
57 kDa including tags -
Amino acids
1 to 493 -
Tags
His tag N-Terminus -
Additional sequence information
NP_000276.
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab202165 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Additional notes
This product was previously labelled as PEPD
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 89% PBS, 10% Glycerol (glycerin, glycerine), 0.02% DTT
General Info
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Alternative names
- Aminoacyl L proline hydrolase
- Imidodipeptidase
- MGC10905
see all -
Function
Splits dipeptides with a prolyl or hydroxyprolyl residue in the C-terminal position. Plays an important role in collagen metabolism because the high level of iminoacids in collagen. -
Involvement in disease
Defects in PEPD are a cause of prolidase deficiency (PD) [MIM:170100]. Prolidase deficiency is an autosomal recessive disorder associated with iminodipeptiduria. The clinical phenotype includes skin ulcers, mental retardation, recurrent infections, and a characteristic facies. These features, however are incompletely penetrant and highly variable in both age of onset and severity. There is a tight linkage between the polymorphisms of prolidase and the myotonic dystrophy trait. -
Sequence similarities
Belongs to the peptidase M24B family. Eukaryotic-type prolidase subfamily. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab202165 has not yet been referenced specifically in any publications.