The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activitySpecific activity: approximately 230-310 pmole/min/µg.
Enzymatic activity was confirmed by measuring the remaining peroxide after incubation of PRDX4 and peroxide for 20 min at room temperature. Specific activity is defined as the amount of hydroperoxide that 1µg of enzyme can reduce at 25°C for 1 minute.
Additional notesShould be stored desiccated.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 8.00 Constituents: 10% Glycerol, 0.32% Tris HCl
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Antioxidant enzyme 372
Antioxidant enzyme AOE372
Thioredoxin dependent peroxide reductase A0372
Thioredoxin Peroxidase (Antioxidant Enzyme)
Thioredoxin peroxidase AO372
Thioredoxin-dependent peroxide reductase A0372
FunctionProbably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
Sequence similaritiesBelongs to the ahpC/TSA family. Contains 1 thioredoxin domain.