Recombinant human Peroxiredoxin 4 protein (ab117192)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MWETEERPRT REEECHFYAG GQVYPGEASR VSVADHSLHL SKAKISKPAP YWEGTAVIDG EFKELKLTDY RGKYLVFFFY PLDFTFVCPT EIIAFGDRLE EFRSINTEVV ACSVDSQFTH LAWINTPRRQ GGLGPIRIPL LSDLTHQISK DYGVYLEDSG HTLRGLFIID DKGILRQITL NDLPVGRSVD ETLRLVQAFQ YTDKHGEVCP AGWKPGSETI IPDPAGKLKY FDKLN
    • Molecular weight
      29 kDa including tags
    • Amino acids
      38 to 271
    • Tags
      His tag N-Terminus
    • Additional sequence information
      PRDX4 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 255 amino acids (38-271 a.a.).

Specifications

Our Abpromise guarantee covers the use of ab117192 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Specific activity: approximately 230-310 pmole/min/µg.
    Enzymatic activity was confirmed by measuring the remaining peroxide after incubation of PRDX4 and peroxide for 20 min at room temperature.
    Specific activity is defined as the amount of hydroperoxide that 1µg of enzyme can reduce at 25°C for 1 minute.
  • Applications

    SDS-PAGE

    Functional Studies

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Liquid
  • Additional notes
    Should be stored desiccated.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 10% Glycerol, 0.32% Tris HCl

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Antioxidant enzyme 372
    • Antioxidant enzyme AOE372
    • AOE37 2
    • AOE37-2
    • AOE372
    • EC 1.11.1.15
    • Peroxiredoxin IV
    • Peroxiredoxin-4
    • Peroxiredoxin4
    • PRDX 4
    • Prdx4
    • PRDX4_HUMAN
    • PRX 4
    • Prx IV
    • Prx-IV
    • PRX4
    • PrxIV
    • Thioredoxin dependent peroxide reductase A0372
    • Thioredoxin peroxidase
    • Thioredoxin Peroxidase (Antioxidant Enzyme)
    • Thioredoxin peroxidase AO372
    • Thioredoxin-dependent peroxide reductase A0372
    • TRANK
    see all
  • Function
    Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
  • Sequence similarities
    Belongs to the ahpC/TSA family.
    Contains 1 thioredoxin domain.
  • Cellular localization
    Cytoplasm. Secreted.
  • Information by UniProt

References for Recombinant human Peroxiredoxin 4 protein (ab117192)

ab117192 has not yet been referenced specifically in any publications.

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