Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      AQPPRLSRSGASSLWDPASPAPTSGPRPRLWEGQDVLARWTDGLLYLGTI KKVDSAREVCLVQFEDDSQFLVLWKDISPAALPGEELLCCVCRSETVVP
    • Molecular weight
      37 kDa including tags
    • Amino acids
      2 to 100

Specifications

Our Abpromise guarantee covers the use of ab114620 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

General Info

  • Alternative names
    • hPCl1
    • MTF2 L2
    • MTF2L 2
    • MTF2L2
    • PCL 1
    • PCL1
    • PHD finger protein 1
    • PHD finger protein1
    • PHF 1
    • PHF 2
    • Phf1
    • PHF1_HUMAN
    • PHF2
    • Plc 1
    • Plc1
    • Polycomb like protein 1
    • Polycomb like protein1
    • Polycomb-like protein 1
    • Protein PHF1
    • T complex testis expressed 3
    • T complex testis expressed3
    • Tctex 3
    • Tctex3
    see all
  • Function
    Transcriptional repressor. May promote methylation of histone H3 on 'Lys-27' by the PRC2/EED-EZH2 complex.
  • Tissue specificity
    Highest levels in heart, skeletal muscle, and pancreas, lower levels in brain, placenta, lung, liver and kidney.
  • Sequence similarities
    Contains 2 PHD-type zinc fingers.
  • Cellular localization
    Nucleus. Localizes specifically to the promoters of numerous target genes.
  • Information by UniProt

Images

  • ab114620 analysed on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab114620 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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