Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab89857 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityThe specific activity of ab89857 was determined to be 70 nmol/min/mg.
  • Applications

    SDS-PAGE

    Functional Studies

  • FormLiquid
  • Additional notes

    ab204885 (ZIP Kinase peptide substrate) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • GSD9C
    • PHK gamma LT
    • PHK gamma T
    • Phosphorylase b kinase gamma catalytic chain testis/liver isoform
    • Phosphorylase b kinase gamma catalytic chain, liver/testis isoform
    • Phosphorylase kinase gamma subunit 2
    • Phosphorylase kinase subunit gamma 2
    • Phosphorylase kinase, gamma 2 (testis)
    • Phosphorylase kinase, gamma 2 (testis/liver)
    • PSK C3
    • Serine/threonine protein kinase PHKG2
    see all
  • RelevanceMutations in PHKG2 along with PHKA2 and PHKB, all three different genes of phosphorylase kinase (Phk) subunits, can give rise to glycogen storage disease of the liver. The autosomal-recessive, liver-specific variant of Phk deficiency is caused by mutations in the gene encoding the testis/liver isoform of the catalytic gamma subunit, PHKG2.
  • Cellular localizationCytoplasmic

Recombinant human PHKG2 protein images

  • Kinase Assay demonstrating specific activity of ab89857
  • SDS-PAGE showing ab89857 at approximately 70kDa

References for Recombinant human PHKG2 protein (ab89857)

ab89857 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"