The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProduct is NOT sterile! Please filter the product by an appropriate sterile filter before using it in cell culture.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Constituents: 0.01M Tris buffer, pH 8.6
ReconstitutionAdd deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely.
Group XII secreted phospholipase A2
Group XIIA secreted phospholipase A2
Group XIIA secretory phospholipase A2
Group XIIA secretory phospholipase A2 precursor
phosphatidylcholine 2 acylhydrolase 12A
Phosphatidylcholine 2 acylhydrolase GXII
Phosphatidylcholine 2-acylhydrolase 12A
Phospholipase A2 group XIIA
FunctionPA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine.
Tissue specificityAbundantly expressed in heart, skeletal muscle, kidney, liver and pancreas.
Sequence similaritiesBelongs to the phospholipase A2 family.