The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Phosphorylase b kinase regulatory subunit beta
Phosphorylase kinase B
Phosphorylase kinase beta polypeptide
Phosphorylase kinase beta subunit
Phosphorylase kinase subunit beta
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
Glycan biosynthesis; glycogen metabolism.
Involvement in disease
Glycogen storage disease 9B
Belongs to the phosphorylase b kinase regulatory chain family.
Ser-701 is probably phosphorylated by PKA. Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.