Recombinant Human Phosphoserine phosphatase protein (ab48755)

Overview

  • Product name
    Recombinant Human Phosphoserine phosphatase protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MVSHSELRKL FYSADAVCFD VDSTVIREEG IDELAKICGV EDAVSEMTRR AMGGAVPFKA ALTERLALIQ PSREQVQRLI AEQPPHLTPG IRELVSRLQE RNVQVFLISG GFRSIVEHVA SKLNIPATNV FANRLKFYFN GEYAGFDETQ PTAESGGKGK VIKLLKEKFH FKKIIMIGDG ATDMEACPPA DAFIGFGGNV IRQQVKDNAK WYITDFVELL GELEE
    • Amino acids
      1 to 225

Specifications

Our Abpromise guarantee covers the use of ab48755 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    Recombinant human Phosphoserine phosphatase was overexpressed in E. coli and purified by conventional chromatography.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20mM HEPES, 100mM Potassium chloride, 1mM DTT, pH 7.5

General Info

  • Alternative names
    • EC 3.1.3.3
    • L 3 phosphoserine phosphatase
    • L-3-phosphoserine phosphatase
    • O phosphoserine phosphohydrolase
    • O-phosphoserine phosphohydrolase
    • Phosphoserine phosphatase
    • Phosphoserine phosphatase deficiency, included
    • PSP
    • PSPase
    • Psph
    • PSPHD
    • SERB_HUMAN
    see all
  • Function
    Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates.
  • Pathway
    Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3.
  • Involvement in disease
    Defects in PSPH are the cause of phosphoserine phosphatase deficiency (PSPHD)[MIM:614023]. A disorder that results in pre- and postnatal growth retardation, moderate psychomotor retardation and facial features suggestive of Williams syndrome.
  • Sequence similarities
    Belongs to the SerB family.
  • Information by UniProt

Images

  • 14% SDS-PAGE gel loaded with ab48755
    recombinant human Phosphoserine phosphatase, M.Wt. 25kDa

References

ab48755 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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