Recombinant Human PI 3 Kinase catalytic subunit gamma (mutated D946 A) protein (ab91392)

Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab91392 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    Affinity purified.
  • FormLiquid
  • Additional notes


    The PI 3 Kinase catalytic subunit gamma D946A protein is a catalytically inactive mutant of PI 3 Kinase with a D946A mutation in the ATP binding site.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 50% Glycerol, 50mM Sodium chloride, 25mM Tris HCl, 0.5mM Magnesium chloride, pH 8.0

General Info

  • Alternative names
    • 1 phosphatidylinositol 3 kinase
    • 5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma
    • 5-bisphosphate 3-kinase catalytic subunit gamma isoform
    • p110 gamma
    • p110gamma
    • p120 PI3K
    • p120-PI3K
    • Phosphatidylinositol 3 kinase catalytic 110 kD gamma
    • Phosphatidylinositol 3 kinase gamma, p110 gamma
    • Phosphatidylinositol 3 kinase, catalytic, gamma polypeptide
    • Phosphatidylinositol 4 5 bisphosphate 3 kinase 110 kDa catalytic subunit gamma
    • Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit gamma
    • Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit gamma isoform
    • Phosphatidylinositol-4
    • Phosphoinositide 3 kinase catalytic gamma polypeptide
    • Phosphoinositide 3 kinase gamma catalytic subunit
    • PI3 kinase p110 subunit gamma
    • PI3-kinase subunit gamma
    • PI3CG
    • PI3K
    • PI3K-gamma
    • PI3Kgamma
    • PIK3
    • Pik3cg
    • PK3CG_HUMAN
    • PtdIns-3-kinase subunit gamma
    • PtdIns-3-kinase subunit p110-gamma
    • Serine/threonine protein kinase PIK3CG
    see all
  • Function3-phosphorylates the cellular phosphoinositide PtdIns-4,5-biphosphate (PtdIns(4,5)P2) to produce PtdIns-3, 4,5-triiphosphate (PtdIns(3,4,5)P3). Links G-protein coupled receptor activation to the secondary messenger PtdIns(3,4,5)P3 production.
  • Tissue specificityPancreas, skeletal muscle, liver and heart.
  • PathwayPhospholipid metabolism; phosphatidylinositol phosphate biosynthesis.
  • Sequence similaritiesBelongs to the PI3/PI4-kinase family.
    Contains 1 PI3K/PI4K domain.
  • Information by UniProt

References for Recombinant Human PI 3 Kinase catalytic subunit gamma (mutated D946 A) protein (ab91392)

ab91392 has not yet been referenced specifically in any publications.

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