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Source Baculovirus infected Sf9 cells
Amino Acid Sequence
Molecular weight 121 kDa including tags
Amino acids 1 to 1102
Tags His tag N-Terminus Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activity The specific activity of ab125538 was determined to be 52 nmol/min/mg.
Purity > 85
% Densitometry. Purity determined to be >85% by densitometry.
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Preservative: 1.02% Imidazole Constituents: 0.002% PMSF, 0.81% Sodium phosphate, 0.004% DTT, 25% Glycerol, 1.75% Sodium chloride
This product is an active protein and may elicit a biological response in vivo, handle with caution.
1 phosphatidylinositol 3 kinase
5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma
5-bisphosphate 3-kinase catalytic subunit gamma isoform
Function 3-phosphorylates the cellular phosphoinositide PtdIns-4,5-biphosphate (PtdIns(4,5)P2) to produce PtdIns-3, 4,5-triiphosphate (PtdIns(3,4,5)P3). Links G-protein coupled receptor activation to the secondary messenger PtdIns(3,4,5)P3 production.
Tissue specificity Pancreas, skeletal muscle, liver and heart.
Pathway Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis.
Sequence similarities Belongs to the PI3/PI4-kinase family. Contains 1 PI3K/PI4K domain.
Information by UniProt
Recombinant human PI 3 Kinase catalytic subunit gamma protein images
References for Recombinant human PI 3 Kinase catalytic subunit gamma protein (ab125538)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"