Recombinant human PI 3 Kinase p110 delta protein (ab68613)

Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab68613 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Activity: 3 nmol/mg/min using phosphatidylinositol as the substrate.
  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    This protein was purified by affinity chromatography.
  • Form
    Liquid
  • Additional notes
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50% Glycerol, 50mM Sodium chloride, 25mM Tris, 0.5mM Magnesium chloride, pH 8.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta
    • 5-bisphosphate 3-kinase catalytic subunit delta isoform
    • APDS
    • GRB1
    • IMD14
    • p110d
    • p110delta
    • p110dp85a
    • p85-ALPHA
    • Phosphatidylinositol 3 kinase catalytic delta polypeptide
    • Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta isoform
    • Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit delta
    • Phosphatidylinositol 4,5 bisphosphate 3 kinase, catalytic subunit delta
    • Phosphatidylinositol 45 bisphosphate 3 kinase catalytic subunit delta isoform
    • Phosphatidylinositol-4
    • Phosphoinositide 3 kinase B
    • Phosphoinositide 3 kinase C
    • Phosphoinositide 3 kinase catalytic delta polypeptide
    • Phosphoinositide 3 kinase, catalytic, delta polypeptide variant p37delta
    • PI3 kinase p110 subunit delta
    • PI3-kinase subunit delta
    • PI3K
    • PI3K-delta
    • PI3Kdelta
    • Pik3cd
    • PIK3R1
    • PK3CD
    • PK3CD_HUMAN
    • PtdIns 3 kinase p110
    • PtdIns 3 kinase subunit p110 delta
    • PtdIns-3-kinase subunit delta
    • PtdIns-3-kinase subunit p110-delta
    see all
  • Tissue specificity
    Expressed predominantly in leukocytes.
  • Pathway
    Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis.
  • Sequence similarities
    Belongs to the PI3/PI4-kinase family.
    Contains 1 PI3K/PI4K domain.
  • Post-translational
    modifications
    Autophosphorylation on Ser-1039 results in the almost complete inactivation of the lipid kinase activity.
  • Information by UniProt

References

ab68613 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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