The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
PI3 kinase p85 subunit alpha
PI3 kinase p85 subunit beta
PI 3-Kinase is a dimer composed of an 85kD subunit and a 110kD subunit. At least three genes (a, b and g) are known to encode the 85kD subunit, which has no catalytic activity and is thought to regulate the kinase activity of the 110kD catalytic subunit. Two SH2 domains are located at the C-terminus of the 85kD subunit, which have been shown to bind receptors and intracellular proteins phosphorylated on tyrosine. The N-terminal region of the 85kD subunit contains a SH3 domain. Recent evidence suggests that PI 3-Kinase may be involved in directing activated receptor trafficking.
ab159130 on a 12.5% SDS-PAGE stained with Coomassie Blue.
has not yet been referenced specifically in any publications.
Publishing research using ab159130? Please let us know so that we can cite the reference in this datasheet.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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