Recombinant human PI3 Kinase p110 beta + PI3 Kinase p85 beta protein (ab125571)

Overview

  • Product name
    Recombinant human PI3 Kinase p110 beta + PI3 Kinase p85 beta protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab125571 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    The specific activity of ab125571 was determined to be 28 nmol/min/mg.
  • Applications

    Western blot

    Functional Studies

    SDS-PAGE

  • Purity
    > 70 % Densitometry.
    Purity determined to be >70% by densitometry.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.00
    Preservative: 1.02% Imidazole
    Constituents: 0.002% PMSF, 0.81% Sodium phosphate, 0.004% DTT, 25% Glycerol, 1.75% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • p110beta
    • p85
    • p85 beta
    • P85B
    • Phosphatidylinositol 3 kinase 85 kDa regulatory subunit beta
    • Phosphatidylinositol 3 kinase regulatory subunit beta
    • Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit beta
    • Phosphatidylinositol 4,5 bisphosphate 3 kinase catalytic subunit beta isoform
    • Phosphoinositide 3 kinase regulatory subunit 2
    • Phosphoinositide 3 kinase regulatory subunit 2 (beta)
    • PI3 kinase regulatory subunit beta
    • PI3 kinase subunit beta
    • PI3 kinase subunit p85-beta
    • PI3K beta
    • PI3K regulatory subunit beta
    • PI3Kbeta
    • PIK3C1
    • PIK3CB
    • PIK3R2
    • PtdIns 3 kinase regulatory subunit beta
    • PtdIns 3 kinase regulatory subunit p85 beta
    • PtdIns 3 kinase subunit beta
    • PtdIns 3 kinase subunit p110 beta
    see all
  • Relevance
    PI3 Kinase p110 beta: Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. PI3 Kinase p85 beta: Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.

Images

  • SDS-PAGE analysis of ab125571. The upper arrow corresponds to PI3 Kinase p110 beta at 111 kDa. The lower arrow corresponds to PI3 Kinase p85 beta at 88 kDa.
  • The specific activity of ab125571 was determined to be 28 nmol/min/mg.

References

ab125571 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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