Recombinant human PI4K2A protein (ab102109)

Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • AccessionQ9BTU6
    • SpeciesHuman
    • Molecular weight79 kDa including tags
    • Amino acids1 to 479

Specifications

Our Abpromise guarantee covers the use of ab102109 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activitySpecific activity is 95 nmol/min/mg
  • Applications

    SDS-PAGE

    Functional Studies

  • Purity> 95 % SDS-PAGE.
    ab102109 is >95% pure as determined by densitometry.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Phosphatidylinositol 4 kinase type 2 alpha
    • Phosphatidylinositol 4 kinase type II alpha
    • PI4KII
  • RelevanceTogether with PI4K2B and the type III PI4Ks (PIK4CA and PIK4CB) PI4K2A contributes to the overall PI4 kinase activity of the cell. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells
  • Cellular localizationCytoplasm. Membrane. Note: Found in subdomains of the plasma membrane termed non caveolar membrane rafts.

Recombinant human PI4K2A protein images

  • ab102109 was determined to be >95% pure as assessed by densitometry. The predicted molecular weight is ~79 kDa.
  • ab102109 has a specific activity of 95 nmol/min/mg.

References for Recombinant human PI4K2A protein (ab102109)

ab102109 has not yet been referenced specifically in any publications.

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