Recombinant Human PKA regulatory subunit I beta protein (ab102106)

Overview

  • Product name
    Recombinant Human PKA regulatory subunit I beta protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      52 kDa including tags
    • Amino acids
      1 to 381
    • Tags
      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab102106 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

  • Purity
    > 90 % SDS-PAGE.
    ab102106 is >90% pure as determined by densitometry.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: 150mM Imidazole
    Constituents: 25% Glycerol, 50mM Tris HCl, 50mM Sodium phosphate, 300mM Sodium chloride, 2mM DTT, 0.1mM PMSF, pH 7.0

General Info

  • Alternative names
    • cAMP dependent protein kinase type I beta regulatory subunit
    • cAMP-dependent protein kinase type I-beta regulatory subunit
    • KAP1_HUMAN
    • PKARI beta
    • PRKAR 1
    • PRKAR 1B
    • PRKAR1
    • Prkar1b
    • PRKAR1B protein
    • Protein kinase cAMP dependent regulatory type I beta
    • RIbeta
    see all
  • Tissue specificity
    Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
  • Sequence similarities
    Belongs to the cAMP-dependent kinase regulatory chain family.
    Contains 2 cyclic nucleotide-binding domains.
  • Post-translational
    modifications
    The pseudophosphorylation site binds to the substrate-binding region of the catalytic chain, resulting in the inhibition of its activity.
  • Information by UniProt

Images

  • ab102106 was determined to be >90% pure by densitometry. The predicted molecular weight is 52 kDa.

References

ab102106 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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