Recombinant Human PLEKHM2 protein (ab161570)

Overview

  • Product name
    Recombinant Human PLEKHM2 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MVHSSEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVL LTDCYVYLLRKGATEKPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRK QFLLDTADVALAEFFLASLKSAMIKGCREPPYPSILTDATMEKLALAKFV AQESKCEASAVTVRFYGLVHWEDPTDESLGPTPCHCSPPEGTITKEGMLH YKAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGEQCGGC RRANTTDRPHAFQVILSDRPCLELSAESEAEMAEWMQHLCQAVSKGVIPQ GVAPSPCIPCCLVLTDDRLFTCHEDCQTSFFRSLGTAKLGDISAVSTEPG KEYCVLEFSQDSQQLLPPWVIYLSCTSELDRLLSALNSGWKTIYQVDLPH TAIQEASNKKKFEDALSLIHSAWQRSDSLCRGRASRDPWC
    • Amino acids
      1 to 440
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab161570 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • KIAA0842
    • Novel RUN and PH domain containing protein
    • PH domain containing family M member 2
    • Pleckstrin homology domain containing family M (with RUN domain) member 2
    • Pleckstrin homology domain containing family M member 2
    • PLEKHM 2
    • RP11 169K16.1
    • Salmonella induced filaments A and kinesin interacting protein
    • SifA (Salmonella induced filaments A) and kinesin interacting protein
    • SifA and kinesin interacting protein
    • SKIP
    see all
  • Relevance
    PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.
  • Cellular localization
    Cytoplasmic

Images

  • ab161570 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab161570 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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