Overview

  • Product nameRecombinant Human POLR2E protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman

Associated products

Specifications

Our Abpromise guarantee covers the use of ab81886 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

General Info

  • Alternative names
    • and III subunit ABC1
    • and III subunit RPABC1
    • DNA directed RNA polymerase II 23 kDa polypeptide
    • DNA directed RNA polymerase II polypeptide E
    • DNA directed RNA polymerase II subunit E
    • DNA directed RNA polymerases I II and III subunit RPABC1
    • DNA-directed RNA polymerase II 23 kDa polypeptide
    • DNA-directed RNA polymerase II subunit E
    • DNA-directed RNA polymerases I
    • hRPB25
    • hsRPB5
    • II
    • Polr2e
    • Polymerase (RNA) II (DNA directed) polypeptide E (25kD)
    • Polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
    • RNA polymerases I
    • RNA polymerases I, II, and III subunit ABC1
    • RPAB1_HUMAN
    • RPABC1
    • RPB5
    • RPB5 homolog
    • XAP4
    see all
  • FunctionDNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
  • Sequence similaritiesBelongs to the archaeal rpoH/eukaryotic RPB5 RNA polymerase subunit family.
  • Cellular localizationNucleus.
  • Information by UniProt

References for Recombinant Human POLR2E protein (ab81886)

ab81886 has not yet been referenced specifically in any publications.

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