Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab81845 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -20ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

General Info

  • Alternative names
    • DNA directed RNA polymerase II 14.4 kda polypeptide
    • DNA directed RNA polymerase II polypeptide F
    • DNA directed RNA polymerases I, II, and III 14.4 kDa polypeptide
    • HRBP14.4
    • hsRPB6
    • POLRF
    • polymerase (RNA) II (DNA directed) polypeptide F
    • RPABC14.4
    • RPABC2
    • RPB14.4
    • RPB6
    see all
  • Relevance
    POLR2F belongs to the archaeal rpoK/eukaryotic RPB6 RNA polymerase subunit family and is the sixth largest subunit of RNA polymerase II. This polymerase, along with two other DNA-directed RNA polymerases, is responsible for synthesizing messenger RNA in eukaryotes. Three distinct zinc-containing RNA polymerases are found in eukaryotic nuclei: polymerase I for the ribosomal RNA precursor, polymerase II for the mRNA precursor, and polymerase III for 5S and tRNA genes. Each class of RNA polymerase is assembled from 9 to 15 different polypeptides. In yeast, this polymerase subunit, in combination with at least two other subunits, forms a structure that stabilizes the transcribing polymerase on the DNA template.
  • Cellular localization
    Nuclear

References

ab81845 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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