Recombinant Human PPAR alpha protein (ab82045)



  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • Amino acids170 to 468


Our Abpromise guarantee covers the use of ab82045 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityThe protein has been tested in a SRC1 interaction assay and has been found to be ligand dependent.
  • Applications


  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Additional notesThe protein has been tested in a SRC1 interaction assay and has been found to be ligand dependent.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

General Info

  • Alternative names
    • hPPAR
    • MGC2237
    • MGC2452
    • NR1C1
    • Nuclear receptor subfamily 1 group C member 1
    • OTTHUMP00000197740
    • OTTHUMP00000197741
    • Peroxisome proliferative activated receptor alpha
    • Peroxisome proliferator activated receptor alpha
    • Peroxisome proliferator-activated receptor alpha
    • PPAR
    • PPAR-alpha
    • ppara
    • PPARalpha
    see all
  • FunctionLigand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.
  • Tissue specificitySkeletal muscle, liver, heart and kidney.
  • Sequence similaritiesBelongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt

References for Recombinant Human PPAR alpha protein (ab82045)

ab82045 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your email, and I sincerely apologize for the extended delay in resolving this problem.

I have been unable to obtain the lab protocol for the binding assay with ab82045, and due to this lack of information we may remove the prot...

Read More

Thank you for your reply.

Yes, we will be sending a vial of the protein from a new lot.

We apprecipate your patience!

Thank you for your reply.

I apologize that we sent the incorrect information. I've asked the lab for the correct protocol, which I will forward to you as soon as possible. I am sorry for the delay and I will be back in touch shortly.
Read More

Thank you for your call last week and for your patience while I have been in touch with the production lab regarding this protein.

Each lot is not tested in a binding assay, and the binding information was determined when the protein was init...

Read More