Recombinant Human PPAR delta protein (ab82033)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Amino acids
      165 to 441

Specifications

Our Abpromise guarantee covers the use of ab82033 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

General Info

  • Alternative names
    • FAAR
    • MGC3931
    • NR1C2
    • NUC1
    • NUCI
    • NUCII
    • Nuclear hormone receptor 1
    • Nuclear receptor subfamily 1 group C member 2
    • Peroxisome proliferative activated receptor delta
    • Peroxisome proliferator-activated receptor beta
    • Peroxisome proliferator-activated receptor beta (PPAR-beta)
    • Peroxisome proliferator-activated receptor delta
    • PPAR beta
    • PPAR-beta
    • PPAR-delta
    • PPAR-ß
    • PPARB
    • ppard
    • PPARD_HUMAN
    see all
  • Function
    Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.
  • Tissue specificity
    Ubiquitous with maximal levels in placenta and skeletal muscle.
  • Sequence similarities
    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References

ab82033 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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