Recombinant Human PPP2R1A protein (ab207146)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant Human PPP2R1A protein
See all PPP2R1A proteins and peptides -
Purity
> 90 % SDS-PAGE.
ab207146 was purified using conventional chromatography techniques. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MGSSHHHHHHSSGLVPRGSHMGSMAAADGDDSLYPIAVLIDELRNEDVQL RLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFT TLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAH FVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDD TPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEA CVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPE ITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQIL PCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDEC PEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYM PLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEW AHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLR MAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKY FAQEALTVLSLA -
Predicted molecular weight
68 kDa including tags -
Amino acids
1 to 589 -
Tags
His tag N-Terminus -
Additional sequence information
NP_055040.
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab207146 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 90% PBS, 10% Glycerol (glycerin, glycerine)
General Info
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Alternative names
- 2AAA_HUMAN
- 6330556D22Rik
- Alpha isoform of regulatory subunit A, protein phosphatase
see all -
Function
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis. -
Sequence similarities
Belongs to the phosphatase 2A regulatory subunit A family.
Contains 15 HEAT repeats. -
Domain
Each HEAT repeat appears to consist of two alpha helices joined by a hydrophilic region, the intrarepeat loop. The repeat units may be arranged laterally to form a rod-like structure. -
Cellular localization
Cytoplasm. Chromosome > centromere. Centromeric localization requires the presence of BUB1. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab207146 has not yet been referenced specifically in any publications.