Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionP24158
    • SpeciesHuman
    • SequenceMAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGN PGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHF SVAQVFLNNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQPVPHGT QCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICF GDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRV EAKGRP
    • Molecular weight54 kDa including tags
    • Amino acids1 to 256
    • TagsGST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab112346 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityuseful for Antibody Production and Protein Array
  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • FormLiquid
  • Additional notesuseful for Antibody Production and Protein Array
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl
    Note: Glutathione is reduced

General Info

  • Alternative names
    • ACPA
    • AGP 7
    • AGP7
    • AGP7 serine proteinase
    • Azurophil Granule Protein 7
    • C ANCA
    • C ANCA antigen
    • C-ANCA antigen
    • CANCA
    • EC 3.4.21.76
    • Leukocyte proteinase 3
    • MBN
    • MBT
    • MBT WEGENER AUTOANTIGEN
    • Myeloblastin
    • Neutrophil proteinase 4
    • NP 4
    • NP-4
    • NP4
    • P29
    • PR 3
    • PR-3
    • PR3
    • Proteinase 3
    • Proteinase3
    • PRTN 3
    • Prtn3
    • PRTN3_HUMAN
    • Serine proteinase neutrophil Wegener granulomatosis autoantigen
    • Serine proteinase, neutrophil
    • Wegener autoantigen
    • Wegener granulomatosis autoantigen
    see all
  • FunctionPolymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
  • Sequence similaritiesBelongs to the peptidase S1 family. Elastase subfamily.
    Contains 1 peptidase S1 domain.
  • Information by UniProt

Recombinant Human PR3 protein images

  • 12.5% SDS-PAGE showing ab112346 at approximately 54.23kDa stained with Coomassie Blue.

References for Recombinant Human PR3 protein (ab112346)

ab112346 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"