The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 mg/ml. Best used within three months from the date of receipt.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Lysosomal carboxypeptidase C
Lysosomal Pro X carboxypeptidase
Lysosomal Pro-X carboxypeptidase
Prolylcarboxypeptidase (angiotensinase C)
prolylcarboxypeptidase isoform 1 preproprotein
FunctionCleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
Tissue specificityHighest levels in placenta, lung and liver. Also present in heart, brain, pancreas and kidney.
Sequence similaritiesBelongs to the peptidase S28 family.