The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Heterogeneous nuclear ribonucleoprotein methyltransferase like protein 4
Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4
HMT1 hnRNP methyltransferase like 3
HMT1 hnRNP methyltransferase like 4
Protein arginine N methyltransferase 4
Protein arginine N methyltransferase 8
Protein arginine N-methyltransferase 8
Membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA). Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS.
Belongs to the protein arginine N-methyltransferase family. PRMT8 subfamily.
The SH3-binding motifs mediate the interaction with SH3 domain-containing proteins such as PRMT2 and FYN, possibly leading to displace the N-terminal domain and activate the protein. The N-terminal region (1-60) inhibits the enzymatic activity.