Recombinant Human Profilin 2 protein (ab40202)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab40202 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: 0.002% Sodium Azide
    Constituents: 3mM Sodium chloride, 10mM Tris, 2.5mM Imidazole, pH 8.

General Info

  • Alternative names
    • D3S1319E
    • PFL
    • PFN 2
    • Pfn2
    • PROF2_HUMAN
    • Profilin II
    • Profilin-2
    • Profilin2
    • ProfilinII
    see all
  • FunctionBinds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
  • Tissue specificityHighly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.
  • Sequence similaritiesBelongs to the profilin family.
  • Cellular localizationCytoplasm > cytoskeleton.
  • Information by UniProt

References for Recombinant Human Profilin 2 protein (ab40202)

ab40202 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"