Recombinant Human Profilin 2 protein (ab95291)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MAGWQSYVDN LMCDGCCQEA AIVGYCDAKY VWAATAGGVF QSITPIEIDM IVGKDREGFF TNGLALGAKK CSVIRDSLYV DGDCTMDIRT KSQGGEPTYN VAVGRAGRVL VFVMGKEGVH GGGLNKKAYS MAKYLRDSGF

Specifications

Our Abpromise guarantee covers the use of ab95291 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    ab95291 was purified using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0

General Info

  • Alternative names
    • D3S1319E
    • PFL
    • PFN 2
    • Pfn2
    • PROF2_HUMAN
    • Profilin II
    • Profilin-2
    • Profilin2
    • ProfilinII
    see all
  • Function
    Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
  • Tissue specificity
    Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.
  • Sequence similarities
    Belongs to the profilin family.
  • Cellular localization
    Cytoplasm > cytoskeleton.
  • Information by UniProt

Recombinant Human Profilin 2 protein images

  • 15% SDS-PAGE analysis of 3µg ab95291

References for Recombinant Human Profilin 2 protein (ab95291)

ab95291 has not yet been referenced specifically in any publications.

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