Recombinant Human Properdin protein (ab114924)

Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionP27918
    • SpeciesHuman
    • SequencePHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGP WGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPC PVDGEWDSWGEWSPCIRRNMKS
    • Molecular weight39 kDa including tags
    • Amino acids213 to 334

Specifications

Our Abpromise guarantee covers the use of ab114924 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

    ELISA

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

General Info

  • Alternative names
    • BFD
    • CFP
    • Complement factor P
    • Complement factor properdin
    • Factor P
    • PFC
    • PFD
    • PROP_HUMAN
    • Properdin
    • Properdin P factor complement
    see all
  • FunctionA positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes.
  • Involvement in diseaseDefects in CFP are the cause of properdin deficiency (PFD) [MIM:312060]. PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III).
  • Sequence similaritiesContains 6 TSP type-1 domains.
  • Cellular localizationSecreted.
  • Information by UniProt

Recombinant Human Properdin protein images

  • 12.5% SDS-PAGE showing ab114924 at approximately 39.05kDa.
    Stained with Coomassie Blue.

References for Recombinant Human Properdin protein (ab114924)

ab114924 has not yet been referenced specifically in any publications.

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