Proteasome (prosome macropain) subunit alpha type 2
Proteasome alpha 2 subunit
Proteasome component C3
Proteasome subunit alpha type 2
Proteasome subunit alpha type-2
Proteasome subunit HC3
FunctionThe proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. PSMA2 may have a potential regulatory effect on another component(s) of the proteasome complex through tyrosine phosphorylation.
Sequence similaritiesBelongs to the peptidase T1A family.
Post-translational modificationsPhosphorylated on tyrosine residues; which may be important for nuclear import.