Recombinant Human Proteasome 20S alpha 3 protein (ab115712)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionP25788
    • SpeciesHuman
    • SequenceMGSSHHHHHHSSGLVPRGSHMSSIGTGYDLSASTFSPDGRVFQVEYAMKA VENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNVDRHVGMAVAG LLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVR PFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKL QMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPK DIREEAEKYAKESLKEEDESDDDNM
    • Molecular weight31 kDa including tags
    • Amino acids1 to 255
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab115712 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry
    MALDI-TOF
  • Purity> 95 % SDS-PAGE.
    ab115712 was purified using conventional chromatography techniques.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol, 0.02% DTT, 0.88% Sodium chloride

General Info

  • Alternative names
    • HC8
    • Macropain subunit C8
    • MGC12306
    • MGC32631
    • Multicatalytic endopeptidase complex subunit C8
    • Proteasome (prosome macropain) subunit alpha type 3
    • Proteasome alpha 3 subunit
    • Proteasome component C8
    • Proteasome subunit alpha type 3
    • Proteasome subunit alpha type-3
    • Proteasome subunit C8
    • PSA3_HUMAN
    • PSC8
    • psmA3
    see all
  • FunctionThe proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2.
  • Sequence similaritiesBelongs to the peptidase T1A family.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt

Recombinant Human Proteasome 20S alpha 3 protein images

  • 15% SDS-PAGE showing ab115712 at approximately 30.6kDa (3µg).

References for Recombinant Human Proteasome 20S alpha 3 protein (ab115712)

ab115712 has not yet been referenced specifically in any publications.

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