Recombinant Human Proteasome 20S beta 7 protein (ab123208)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionQ99436
    • SpeciesHuman
    • SequenceMGSSHHHHHH SSGLVPRGSH MTTIAGVVYK DGIVLGADTR ATEGMVVADK NCSKIHFISP NIYCCGAGTA ADTDMTTQLI SSNLELHSLS TGRLPRVVTA NRMLKQMLFR YQGYIGAALV LGGVDVTGPH LYSIYPHGST DKLPYVTMGS GSLAAMAVFE DKFRPDMEEE EAKNLVSEAI AAGIFNDLGS GSNIDLCVIS KNKLDFLRPY TVPNKKGTRL GRYRCEKGTT AVLTEKITPL EIEVLEETVQ TMDTS
    • Molecular weight28 kDa including tags
    • Amino acids44 to 277
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab123208 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry
    MALDI-TOF
  • Purity> 80 % SDS-PAGE.
    ab123208 is purified by using conventional chromatography. Purity is > 80% by SDS-PAGE.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol

General Info

  • Alternative names
    • Macropain chain Z
    • Multicatalytic endopeptidase complex chain Z
    • Proteasome (prosome macropain) subunit beta type 7
    • Proteasome beta 7 subunit
    • Proteasome catalytic subunit 2
    • Proteasome subunit alpha
    • Proteasome subunit beta 7
    • Proteasome subunit beta type-7
    • Proteasome subunit Z
    • PSB7_HUMAN
    • PSMB7
    • PUP1
    • Z
    see all
  • FunctionThe proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the trypsin-like activity.
  • Tissue specificityExpressed at a low level in colonic mucosa. Up-regulated in colorectal cancer tissues.
  • Sequence similaritiesBelongs to the peptidase T1B family.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt

Recombinant Human Proteasome 20S beta 7 protein images

  • 15% SDS-PAGE analysis of ab123208 (3µg).

References for Recombinant Human Proteasome 20S beta 7 protein (ab123208)

ab123208 has not yet been referenced specifically in any publications.

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