The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
>90% by SDS-PAGE. ab169907 was expressed in E.coli as inclusion bodies. The final product was refolded and chromatographically purified.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituent: 0.32% Tris HCl Note: Contains NaCl, KCl, EDTA, arginine, DTT and glycerol.
Macropain chain Z
Multicatalytic endopeptidase complex chain Z
Proteasome (prosome macropain) subunit beta type 7
Proteasome beta 7 subunit
Proteasome catalytic subunit 2
Proteasome subunit alpha
Proteasome subunit beta 7
Proteasome subunit beta type-7
Proteasome subunit Z
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the trypsin-like activity.
Expressed at a low level in colonic mucosa. Up-regulated in colorectal cancer tissues.