Proteasome (prosome macropain) subunit alpha type 1
Proteasome alpha 1 subunit
Proteasome component C2
Proteasome nu chain
Proteasome subunit alpha type 1
Proteasome subunit alpha type I
Proteasome subunit alpha type-1
Proteasome subunit nu
Protein P30 33K
FunctionThe proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal transduction in the macrophage proteasome (By similarity). Might be involved in the anti-inflammatory response of macrophages during the interaction with C.albicans heat-inactivated cells.
Sequence similaritiesBelongs to the peptidase T1A family.