Recombinant Human Proteasome 20S C2 protein (ab116156)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGSMFRNQYD NDVTVWSPQG RIHQIEYAME AVKQGSATVG LKSKTHAVLV ALKRAQSELA AHQKKILHVD NHIGISIAGL TADARLLCNF MRQECLDSRF VFDRPLPVSR LVSLIGSKTQ IPTQRYGRRP YGVGLLIAGY DDMGPHIFQT CPSANYFDCR AMSIGARSQS ARTYLERHMS EFMECNLNEL VKHGLRALRE TLPAEQDLTT KNVSIGIVGK DLEFTIYDDD DVSPFLEGLE ERPQRKAQPA QPADEPAEKA DEPMEH
    • Molecular weight
      32 kDa including tags
    • Amino acids
      1 to 263
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab116156 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 95 % SDS-PAGE.
    ab116156 is purified using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol, 0.03% DTT, 0.88% Sodium chloride

General Info

  • Alternative names
    • 30 kDa prosomal protein
    • HC 2
    • HC2
    • Macropain subunit C2
    • Macropain subunit nu
    • MGC14542
    • MGC14575
    • MGC14751
    • MGC1667
    • MGC21459
    • MGC22853
    • MGC23915
    • Multicatalytic endopeptidase complex subunit C2
    • NU
    • PROS 30
    • PROS-30
    • PROS30
    • Proteasome (prosome macropain) subunit alpha type 1
    • Proteasome alpha 1 subunit
    • Proteasome component C2
    • Proteasome nu chain
    • Proteasome subunit alpha type 1
    • Proteasome subunit alpha type I
    • Proteasome subunit alpha type-1
    • Proteasome subunit nu
    • Protein P30 33K
    • PSA1_HUMAN
    • PSC 2
    • PSC2
    • PSMA 1
    • psmA1
    see all
  • Function
    The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal transduction in the macrophage proteasome (By similarity). Might be involved in the anti-inflammatory response of macrophages during the interaction with C.albicans heat-inactivated cells.
  • Sequence similarities
    Belongs to the peptidase T1A family.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab116156 at approximately 32 kDa (3µg).

References

ab116156 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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