Recombinant Human Protein phosphatase 1 inhibitor 3C (ab117033)

Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionQ9UQK1
    • SpeciesHuman
    • SequenceDLPPVIPTEQKIEFCISYHANGQVFWDNNDGQNYRIVHVQWKPDGVQTQM APQDCAFHQTSPKTELESTIFGSPRLASGLFPEWQSWGRMENLASYR
    • Molecular weight36 kDa including tags
    • Amino acids221 to 317

Specifications

Our Abpromise guarantee covers the use of ab117033 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • OTTHUMP00000020089
    • Phosphatase 1, regulatory inhibitor subunit 5
    • PP1 subunit R5
    • ppp1r3c
    • PPP1R5
    • PPR3C_HUMAN
    • Protein phosphatase 1 regulatory subunit 3C
    • Protein phosphatase 1 regulatory subunit 5
    • protein phosphatase 1, regulatory (inhibitor) subunit 3C
    • Protein targeting to glycogen
    • PTG
    • R5
    see all
  • FunctionActs as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types.
  • Sequence similaritiesContains 1 CBM21 (carbohydrate binding type-21) domain.
  • DomainThe N-terminal region is required for binding to PP1, the central region is required for binding to glycogen and the C-terminal region is required for binding to glycogen phosphorylase, glycogen synthase and phosphorylase kinase.
  • Post-translational
    modifications
    Ubiquitinated by NHLRC1/malin in a EPM2A/laforin-dependent manner.
  • Information by UniProt

Recombinant Human Protein phosphatase 1 inhibitor 3C images

  • 12.5% SDS-PAGE stained with Coomassie Blue showing ab117033 at approximately 36.30 kDa.

References for Recombinant Human Protein phosphatase 1 inhibitor 3C (ab117033)

ab117033 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab117033.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"