For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
Recombinant Human PRUNE protein
Full length protein
Amino Acid Sequence
MEDYLQGCRAALQESRPLHVVLGNEACDLDSTVSALALAFYLAKTTEAEE VFVPVLNIKRSELPLRGDIVFFLQKVHIPESILIFRDEIDLHALYQAGQL TLILVDHHILSKSDTALEEAVAEVLDHRPIEPKHCPPCHVSVELVGSCAT LVTERILQGAPEILDRQTAALLHGTIILDCVNMDLKIGKATPKDSKYVEK LEALFPDLPKRNDIFDSLQKAKFDVSGLTTEQMLRKDQKTIYRQGVKVAI SAIYMDLEAFLQRSNLLADLHAFCQAHSYDVLVAMTIFFNTHNEPVRQLA IFCPHVALQTTICEVLERSHSPPLKLTPASSTHPNLHAYLQGNTQVSRKK LLPLLQEALSAYFDSMKIPSGQPETADVSREQVDKELDRASNSLISGLSQ DEEDPPLPPTPMNSLVDECPLDQGLPKLSAEAVFEKCSQISLSQSTTASL SKK
1 to 453
proprietary tag N-Terminus
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
- Drosophila-related expressed sequence 17
Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1.
Ubiquitously expressed. Seems to be overexpressed in aggressive sarcoma subtypes, such as leiomyosarcomas and malignant fibrous histiocytomas (MFH) as well as in the less malignant liposarcomas.
Belongs to the PPase class C family. Prune subfamily.
Cytoplasm. Nucleus. Cell junction > focal adhesion. In some transfected cells a nuclear staining is also observed.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"