Proteasome (prosome macropain) subunit alpha type 4
Proteasome alpha 4 subunit
Proteasome component C9
Proteasome subunit alpha type 4
Proteasome subunit alpha type-4
Proteasome subunit HC9
Proteasome subunit L
FunctionThe proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Sequence similaritiesBelongs to the peptidase T1A family.
Cellular localizationCytoplasm. Nucleus. Cytoplasm, P-body. Colocalizes with TRIM5 in the cytoplasmic bodies.