Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMAMLRVQPEAQAKVDVFREDLCTKTENLLG SYFPKKISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQ QEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPEIKDVIEQLNL VTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSE RGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDII LKNFEKLKKPRGETKGMIY
    • Molecular weight
      31 kDa including tags
    • Amino acids
      1 to 249
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab99961 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 90 % SDS-PAGE.
    ab99961 is purified using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0

General Info

  • Alternative names
    • 11S regulator complex alpha subunit
    • 11S regulator complex subunit alpha
    • 29 kD MCP activator subunit
    • 29kD MCP activator subunit
    • Activator of multicatalytic protease subunit 1
    • IFI5111
    • IGUP I-5111
    • Interferon gamma IEF SSP 5111
    • Interferon gamma inducible protein 5111
    • Interferon gamma up regulated I 5111 protein
    • Interferon gamma up-regulated I-5111 protein
    • MGC8628
    • PA28a
    • PA28alpha
    • Proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
    • Proteasome activator 28 subunit alpha
    • Proteasome activator complex subunit 1
    • Proteasome activator subunit 1
    • PSME1
    • PSME1_HUMAN
    • REG-alpha
    • REGalpha
    see all
  • Function
    Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
  • Sequence similarities
    Belongs to the PA28 family.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab99961 (3 µg) at approximately 30.8 kDa.

References

ab99961 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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