Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMAKPCGVRLSGEARKQVEVFRQNLFQEAEE FLYRFLPQKIIYLNQLLQEDSLNVADLTSLRAPLDIPIPDPPPKDDEMET DKQEKKEVPKCGFLPGNEKVLSLLALVKPEVWTLKEKCILVITWIQHLIP KIEDGNDFGVAIQEKVLERVNAVKTKVEAFQTTISKYFSERGDAVAKASK ETHVMDYRALVHERDEAAYGELRAMVLDLRAFYAELYHIISSNLEKIVNP KGEEKPSMY
    • Molecular weight
      30 kDa including tags
    • Amino acids
      1 to 239
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab117228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 95 % SDS-PAGE.
    ab117228 is purified using conventional chromatography.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride, 0.02% DTT, 0.002% PMSF

General Info

  • Alternative names
    • 11S regulator complex beta subunit
    • 11S regulator complex subunit beta
    • Activator of multicatalytic protease subunit 2
    • Cell migration inducing protein 22
    • MCP activator 31 kD subunit
    • PA28 beta
    • PA28b
    • PA28beta
    • Proteasome (prosome macropain) activator subunit 2
    • Proteasome (prosome macropain) activator subunit 2 (PA28 beta)
    • Proteasome activator 28 beta
    • Proteasome activator 28 subunit beta
    • Proteasome activator complex subunit 2
    • Proteasome activator hPA28 subunit beta
    • Proteasome activator subunit 2
    • PSME 2
    • PSME2
    • PSME2_HUMAN
    • REG beta
    • REG-beta
    • REGbeta
    see all
  • Function
    Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
  • Sequence similarities
    Belongs to the PA28 family.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab117228 at approximately 29.5kDa (3µg).

References

ab117228 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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