The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Ep3 prostanoid receptor
PGE receptor EP3 subtype
PGE2 receptor EP3 subtype
Prostaglandin E receptor 3
Prostaglandin E receptor 3 (subtype EP3)
Prostaglandin E receptor EP3 subtype 3 isoform
Prostaglandin E2 receptor
Prostaglandin e2 receptor ep3
Prostaglandin E2 receptor EP3 subtype
Prostaglandin receptor (PGE 2)
Prostaglandin receptor 3, EP3, subtype
Prostanoid EP3 receptor
Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems.
Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels.
Belongs to the G-protein coupled receptor 1 family.