Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • Amino acids2 to 167

Specifications

Our Abpromise guarantee covers the use of ab42569 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity1 U/ug. One unit will hydrolyze 1 pmol 6, 8-difluoro-4-methyl umbelliferyl phosphate (DiFMUP) per minute at pH 6.3 and 30?C. Assay buffer: 50 mM Bis-Tris, pH 6.3, 2 mM EDTA, 2 mM DTT, 100 mM DiFMUP.
  • Applications

    Inhibition Assay

  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Additional notes 1 U/ug. One unit will hydrolyze 1 pmol 6, 8-difluoro-4-methyl umbelliferyl phosphate (DiFMUP) per minute at pH 6.3 and 30?C. Assay buffer: 50 mM Bis-Tris, pH 6.3, 2 mM EDTA, 2 mM DTT, 100 mM DiFMUP.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 50% Glycerol, 0.05% Tween 20, 75mM Sodium chloride, 25mM Tris HCl, 2mM EDTA, 10mM Glutathione, 1mM DTT, pH 8

General Info

  • Alternative names
    • BM 008
    • EC 3.1.3.48
    • HH 13
    • HH13
    • HH7 2
    • HU PP 1
    • HUPP 1
    • HUPP1
    • OV 1
    • OV1
    • phosphatase of regenerating liver 2
    • PRL 2
    • PRL2
    • Protein tyrosine phosphatase 4a2
    • protein tyrosine phosphatase IVA
    • protein tyrosine phosphatase IVA2
    • Protein tyrosine phosphatase of regenerating liver 2
    • protein tyrosine phosphatase type IVA 2
    • Protein tyrosine phosphatase type IVA member 2 isoform 1
    • protein tyrosine phosphatase type IVA, member 2
    • PTP (CAAXII)
    • ptp IV1a
    • ptp IV1b
    • PTP4A
    • PTPCAAX2
    • TP4A2_HUMAN
    see all
  • RelevanceProtein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB. Ubiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue.
  • Cellular localizationCell Membrane, Early Endosome and Cytoplasm.

References for Recombinant Human PTP4A2 protein (ab42569)

ab42569 has not yet been referenced specifically in any publications.

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