The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activity1 U/ug. One unit will hydrolyze 1 pmol 6, 8-difluoro-4-methyl umbelliferyl phosphate (DiFMUP) per minute at pH 6.3 and 30?C. Assay buffer: 50 mM Bis-Tris, pH 6.3, 2 mM EDTA, 2 mM DTT, 100 mM DiFMUP.
1 U/ug. One unit will hydrolyze 1 pmol 6, 8-difluoro-4-methyl umbelliferyl phosphate (DiFMUP) per minute at pH 6.3 and 30?C. Assay buffer: 50 mM Bis-Tris, pH 6.3, 2 mM EDTA, 2 mM DTT, 100 mM DiFMUP.
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Preparation and Storage
Stability and Storage
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Protein tyrosine phosphatase of regenerating liver 2
protein tyrosine phosphatase type IVA 2
Protein tyrosine phosphatase type IVA member 2 isoform 1
protein tyrosine phosphatase type IVA, member 2
RelevanceProtein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB. Ubiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue.
Cellular localizationCell Membrane, Early Endosome and Cytoplasm.
References for Recombinant Human PTP4A2 protein (ab42569)
has not yet been referenced specifically in any publications.
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