FunctionImplicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.
Tissue specificityExpression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary.
Sequence similaritiesBelongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily. Contains 1 tyrosine-protein phosphatase domain.
Post-translational modificationsAppears to undergo multiple proteolytic cleavage at consecutive basic residues.