Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMEYKMILVVRNDLKMGKGKVAAQCSHAAVS AYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIALLAHAKMLGLTVSL IQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKLY
    • Molecular weight
      15 kDa including tags
    • Amino acids
      64 to 179
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab101645 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 95 % SDS-PAGE.
    ab101645 was purified using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20mM Tris pH 7.5, 2mM EDTA.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: 0% None
    Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0

General Info

  • Alternative names
    • Bcl 2 inhibitor of transcription 1
    • Bcl-2 inhibitor of transcription 1
    • BIT 1
    • BIT1
    • CGI 147
    • CGI147
    • mitochondrial
    • Peptidyl tRNA hydrolase 2 mitochondrial
    • Peptidyl-tRNA hydrolase 2
    • PTH 2
    • PTH2
    • PTH2_HUMAN
    • PTRH 2
    • PTRH2
    see all
  • Function
    The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
    Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1.
  • Sequence similarities
    Belongs to the PTH2 family.
  • Cellular localization
    Mitochondrion.
  • Information by UniProt

Images

  • ab101645 at 3 µg analysed by 15% SDS PAGE

References

ab101645 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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