Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MPVGTQATMKGITTEQLDALGCRICLGNTYHLGLRPGPELIQKANGLHGF MNWPHNLLTDSGGFQMVSLVSLSEVTEEGVRFRSPYDGNETLLSPEKSVQ IQNALGSDIIMQLDDVVSSTVTGPRVEEAMYRSIRWLDRCIAAHQRPDKQ NLFAIIQGGLDADLRATCLEEMTKRDVPGFAIGGLSGGESKSQFWRMVAL STSRLPKDKPRYLMGVGYATDLVVCVALGCDMFDCVFPTRTARFGSALVP TGNLQLRKKVFEKDFGPIDPECTCPTCQKHSRAFLHALLHSDNTAALHHL TVHNIAYQLQLMSAVRTSIVEKRFPDFVRDFMGAMYGDPTLCPTWATDAL ASVGITLG
    • Amino acids
      1 to 358
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab164380 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • FP3235
    • Guanine insertion enzyme
    • qtrt1
    • Queuine tRNA ribosyltransferase
    • Queuine tRNA ribosyltransferase 1
    • Queuine tRNA-ribosyltransferase
    • TGT
    • TGT, 43 KD subunit
    • TGT, catalytic subunit
    • TGT_HUMAN
    • TGUT
    • tRNA guanine transglycosylase
    • tRNA-guanine transglycosylase
    see all
  • Function
    Interacts with QTRTD1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
  • Pathway
    tRNA modification; tRNA-queuosine biosynthesis.
  • Sequence similarities
    Belongs to the queuine tRNA-ribosyltransferase family.
  • Cellular localization
    Cytoplasm. Mitochondrion. Nucleus. Weakly associates with mitochondria, possibly via QTRTD1.
  • Information by UniProt

Images

  • ab164380 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab164380 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab164380.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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