Queuine tRNA-ribosyltransferase domain-containing protein 1
Queuine tRNA-ribosyltransferase subunit qtrtd1
Interacts with QTRT1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
tRNA modification; tRNA-queuosine biosynthesis.
Belongs to the queuine tRNA-ribosyltransferase family. QTRTD1 subfamily.
Cytoplasm. Mitochondrion. May associate with the mitochondrion outer membrane.