The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 mg/ml. Best used within three months from the date of receipt.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Human quiescin (Q6) mRNA, partial cds
Quiescin Q6 sulfhydryl oxidase 1
Skin sulfhydryl oxidase
Sulfhydryl oxidase 1
Sulfhydryl oxidase 1 precursor
FunctionCatalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. In fibroblasts, it may have tumor-suppressing capabilities being involved in growth regulation.
Tissue specificityExpressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney.
Sequence similaritiesBelongs to the quiescin-sulfhydryl oxidase (QSOX) family. Contains 1 ERV/ALR sulfhydryl oxidase domain. Contains 1 thioredoxin domain.
Cellular localizationGolgi apparatus membrane and Secreted > extracellular space. Found in the extracellular medium of quiescent cells but is not found in proliferating cells.