Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab90187 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityActivity: 100 pmol of protein can bind > 80 pmol of GDP.
  • Applications

    SDS-PAGE

  • Purity> 90 % SDS-PAGE.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25mM HEPES, 2mM DTE (1, 4-Dithioerythritol), 100mM Sodium chloride, 10mM Magnesium chloride, 0.01mM GDP, pH 7.2

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • HRES 1 / RAB4
    • Oncogene RAB4
    • Rab 4
    • RAB 4A
    • RAB4 member RAS oncogene family
    • Rab4a
    • RAB4A member RAS oncogene family
    • RAB4A_HUMAN
    • Ras related protein Rab 4A
    • Ras related protein Rab4A
    • Ras-related protein Rab-4A
    see all
  • FunctionProtein transport. Probably involved in vesicular traffic.
  • Sequence similaritiesBelongs to the small GTPase superfamily. Rab family.
  • Post-translational
    modifications
    Phosphorylated by CDK1 kinase during mitosis.
  • Cellular localizationMembrane. Cytoplasm. Generally associated with membranes. Cytoplasmic when phosphorylated by CDK1.
  • Information by UniProt

References for Recombinant human Rab4 protein (ab90187)

ab90187 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"